Ebolavirus and evidence-based speculations.
نویسندگان
چکیده
منابع مشابه
Ecology of Ebolavirus: A Review of Current Knowledge, Speculations and Future Research Directions
TFiloviruses particularly Ebola and Marburg viruses causes deadly hemorrhagic fevers in humans and non-human primates particularly the great apes (chimpanzees and gorillas). Ebola virus disease (EVD), which is also known as Ebola hemorrhagic fever (EHF) is caused by Ebola virus, which has a case fatality rate of up to 90% [1-3]. Ebola virus is among the most dangerous microorganisms today. It h...
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This clinical review has been developed for The BMJ in collaboration with BMJ Best Practice, based on a regularly updated web/mobile topic that supports evidence-based decision making at the point of care. To view the complete and current version, please refer to the Ebola virus infection topic on the BMJ Best Practice website. Ebola virus disease is a severe, often fatal, zoonotic filovirus in...
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We describe an Ebolavirus minigenome-based system that is suitable for high-throughput screening of compounds able to impair Ebolavirus virus replication and/or transcription. The assay is robust (Z' factor, >0.6) and can be carried out in low-biosafety containment. Results from a pilot screen of 960 compounds are presented.
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arenavirus. Yet the region has seen previous ebolavirus activity (see map). In the mid-1990s, scientists discovered Côte d’Ivoire ebolavirus (now known as Taï Forest ebolavirus) as a cause of a single reported nonfatal case in a researcher who performed a necropsy on an infected chimpanzee. The episode initiated a major research investigation in and around the Taï Forest region — an effort that...
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A network of European biosafety level 4 laboratories has designed the first industry-standard molecular assay for all filoviruses species, based on the strain collections of all participants. It uses 5 optimized L gene primers and 3 probes, as well as an internal control with a separate detection probe. Detection limits (probit analysis, 95% detection chance) were as follows: Zaire ebolavirus, ...
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ورودعنوان ژورنال:
- The new microbiologica
دوره 39 1 شماره
صفحات -
تاریخ انتشار 2016